InterPro : IPR018456

Name  PTR2 family proton/oligopeptide symporter, conserved site Short Name  PTR2_symporter_CS
Type  Conserved_site Description  The transport of peptides into cells is a well-documented biological phenomenon which is accomplished by specific, energy-dependent transporters found in a number of organisms as diverse as bacteria and humans. The PTR family of proteins is distinct from the ABC-type peptide transporters and was uncovered by sequence analyses of a number of recently discovered peptide transport proteins []. These proteins that seem to be mainly involved in the intake of small peptides with the concomitant uptake of a proton [].These integral membrane proteins are predicted to comprise twelvetransmembrane regions.This entry describes two conserved sites. The first conserved site is found within a region that includes the end of the second transmembrane region, a cytoplasmic loop as well as the third transmembrane region. The second conserved site corresponds to the core of the fifth transmembrane region.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

0 Contains

3 Found In

Id Name Short Name Type
IPR020846 Major facilitator superfamily domain MFS_dom Domain
IPR000109 Proton-dependent oligopeptide transporter family POT_fam Family
IPR005279 Amino acid/peptide transporter family AA/pep_transptr Family

0 Parent Features

2 Publications

First Author Title Year Journal Volume Pages
Steiner HY The PTR family: a new group of peptide transporters. 1995 Mol Microbiol 16 825-34
Paulsen IT The POT family of transport proteins. 1994 Trends Biochem Sci 19 404

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)