InterPro : IPR005792

Name  Protein disulphide isomerase Short Name  Prot_disulphide_isomerase
Type  Family Description  This family represents eukaryotic protein disulphide isomerases retained in the endoplasmic reticulum (ER) and other closely related forms. Some members have been assigned alternative or additional functions such as prolyl 4-hydroxylase anddolichyl-diphosphooligosaccharide-protein glycotransferase. Members of this family have at least two protein-disulphide domains, each similar to thioredoxin but with the redox-active disulphide in the motif PWCGHCK, and an ER retention signal at the extreme C terminus (KDEL, HDEL, and similar motifs).

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



1 Child Features

Id Name Short Name Type
IPR017068 Protein disulphide-isomerase A4 Protein_diS-isomerase_A4 Family

3 Contains

Id Name Short Name Type
IPR013766 Thioredoxin domain Thioredoxin_domain Domain
IPR017937 Thioredoxin, conserved site Thioredoxin_CS Conserved_site
IPR005788 Disulphide isomerase Disulphide_isomerase Domain

0 Found In

0 Parent Features

0 Publications

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)