InterPro : IPR006554

Name  Helicase-like, DEXD box c2 type Short Name  Helicase-like_DEXD_c2
Type  Domain Description  This domain of unknown function is found in the Xeroderma pigmentosum group D (XPD) proteins which belong to a family of ATP-dependent helicases characterised by a 'D-E-A-H' motif. This resembles the'D-E-A-D-box' of other known helicases, which represents a special version of the B motif of ATP-binding proteins. In XPD,His replaces the second Asp. The DEAD box helicases are involved invarious aspects of RNA metabolism, including nuclear transcription, pre-mRNA splicing, ribosome biogenesis,nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

1 Contains

Id Name Short Name Type
IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site DNA/RNA_helicase_DEAH_CS Conserved_site

2 Found In

Id Name Short Name Type
IPR013020 DNA helicase (DNA repair), Rad3 type DNA_helicase_DNA-repair_Rad3 Family
IPR001945 Xeroderma pigmentosum group D protein XPGD_DNA_repair Family

1 Parent Features

Id Name Short Name Type
IPR010614 DEAD2 DEAD_2 Domain

0 Publications

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)