InterPro : IPR006515

Name  Polyadenylate binding protein, human types 1, 2, 3, 4 Short Name  PABP_1234
Type  Family Description  These eukaryotic proteins recognise the poly-A of mRNA and consist of four tandem RNA recognition domains at the N terminus followed by a PABP-specific domain at the C terminus. The protein is involved in the transport of mRNAs from the nucleus to the cytoplasm []. There are four paralogs in Homo sapiens(Human) which are expressed in testis [], platelets ([]), broadly expressed ([]) and of unknown tissue range ().
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Sequence Features

GO Displayer

Proteins

InterPro protein domain ID --> Contigs

 

Other

0 Child Features

2 Contains

Id Name Short Name Type
IPR000504 RNA recognition motif domain RRM_dom Domain
IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein PABP_HYD Domain

0 Found In

0 Parent Features

3 Publications

First Author Title Year Journal Volume Pages
Afonina E The human poly(A)-binding protein 1 shuttles between the nucleus and the cytoplasm. 1998 J Biol Chem 273 13015-21
Féral C Human testis expresses a specific poly(A)-binding protein. 2001 Nucleic Acids Res 29 1872-83
Yang H iPABP, an inducible poly(A)-binding protein detected in activated human T cells. 1995 Mol Cell Biol 15 6770-6



To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)