InterPro : IPR008284

Name  Molybdenum cofactor biosynthesis, conserved site Short Name  MoCF_biosynth_CS
Type  Conserved_site Description  Eukaryotic and prokaryotic molybdoenzymes require a molybdopterin cofactor(MoCF) for their activity. The biosynthesis of this cofactor involves acomplex multistep enzymatic pathway. One of the eukaryotic proteins involvedin this pathway is the Drosophila protein cinnamon []which is highly similarto gephyrin, a rat microtubule-associated protein which was thought to anchorthe glycine receptor to subsynaptic microtubules. Cinnamon and gephyrin areevolutionary related, in their N-terminal half, to the Escherichia coliMoCFbiosynthesis proteins mog/chlG and moaB/chlA2.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

0 Contains

4 Found In

Id Name Short Name Type
IPR001453 Molybdopterin binding domain Mopterin-bd_dom Domain
IPR020817 Molybdenum cofactor synthesis Mo_cofactor_synthesis Domain
IPR012245 Molybdenum cofactor biosynthesis protein MoaB MoaB Family
IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria MoaB_proteobac Family

0 Parent Features

1 Publications

First Author Title Year Journal Volume Pages
Kamdar KP The Drosophila molybdenum cofactor gene cinnamon is homologous to three Escherichia coli cofactor proteins and to the rat protein gephyrin. 1994 Genetics 137 791-801

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)