InterPro : IPR012347

Name  Ferritin-related Short Name  Ferritin-rel
Type  Domain Description  This entry represents ferritin and structurally related proteins. Ferritin is a major non-haem iron storage protein in animal, plants and microorganisms []. Iron is required by most organisms, but is potentially toxic due to its reactivity, which is counteracted by sequestering it into ferritin. Ferritin consists of a 4-helical bundle core, and contains a bimetal-ion centre in the middle of the bundle. Other proteins with this structure include: haem-containing bacteriferritins; rubrerythrin, which appears to have a role in anaerobic detoxification pathway for reactive oxygen species []; Dps (DNA-binding proteins from starved cells) used in bacteria for iron storage-detoxification; and CRD1 (AcsF), which is required for the maintenance of photosystem I [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



4 Child Features

Id Name Short Name Type
IPR019243 Domain of unknown function DUF2202 DUF2202 Domain
IPR025419 Domain of unknown function DUF4142 DUF4142 Domain
IPR029447 Domain of unknown function DUF4439 DUF4439 Domain
IPR010287 Domain of unknown function DUF892 DUF892 Domain

1 Contains

Id Name Short Name Type
IPR014034 Ferritin, conserved site Ferritin_CS Conserved_site

12 Found In

Id Name Short Name Type
IPR008331 Ferritin/DPS protein domain Ferritin_DPS_dom Domain
IPR009040 Ferritin- like diiron domain Ferritin-like_diiron Domain
IPR002177 DNA-binding protein Dps DPS_DNA-bd Family
IPR007814 Phenylacetic acid catabolic PaaA_PaaC Family
IPR011882 Phenylacetate-CoA oxygenase, PaaI subunit PA_CoA_Oase3 Family
IPR003251 Rubrerythrin Rubrerythrin Domain
IPR002024 Bacterioferritin Bacterioferritin Family
IPR014490 Uncharacterised conserved protein UCP018063, ferritin fold UCP018063_ferrtn Family
IPR015838 Uncharacterised conserved protein UCP027923, rubrerythrin-type UCP027923_rubrerythrin Family
IPR017040 Uncharacterised conserved protein UCP035918 , rubrerythrin/DUF125-related UCP035918_rubreryth/DUF125 Family
IPR011881 Phenylacetate-CoA oxygenase, PaaG subunit PA_CoA_Oase1 Family
IPR007760 Manganese catalase Mn_catalase Family

1 Parent Features

Id Name Short Name Type
IPR009078 Ferritin-like superfamily Ferritin-like_SF Domain

3 Publications

First Author Title Year Journal Volume Pages
Chiancone E Iron and proteins for iron storage and detoxification. 2004 Biometals 17 197-202
Moseley J The Crd1 gene encodes a putative di-iron enzyme required for photosystem I accumulation in copper deficiency and hypoxia in Chlamydomonas reinhardtii. 2000 EMBO J 19 2139-51
Weinberg MV Rubrerythrin from the hyperthermophilic archaeon Pyrococcus furiosus is a rubredoxin-dependent, iron-containing peroxidase. 2004 J Bacteriol 186 7888-95

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)