InterPro : IPR022749

Name  N6 adenine-specific DNA methyltransferase, N-terminal domain Short Name  D12N6_MeTrfase_N
Type  Domain Description  This domain is found at the N terminus of the methylase subunit of Type I DNA methyltransferases. This domain is found in bacteria and archaea, and is typically between 123 and 138 amino acids in length. It is found in association with . Mutations in this region of EcoKI methyltransferase abolish the normally strong preference of this system for methylating hemimethylated substrate []. The structure of this domain has been shown to be all alpha-helical.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

0 Contains

2 Found In

Id Name Short Name Type
IPR002296 N6 adenine-specific DNA methyltransferase, N12 class N12N6_MeTrfase Family
IPR004546 Restriction endonuclease, type I, HsdM Restrct_endonuc_typeI_HsdM Family

0 Parent Features

1 Publications

First Author Title Year Journal Volume Pages
Kelleher JE Mutations that confer de novo activity upon a maintenance methyltransferase. 1991 J Mol Biol 221 431-40

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)