InterPro : IPR006205

Name  Mevalonate kinase Short Name  Mev_gal_kin
Type  Family Description  Mevalonate kinase () is well-characterised among the Eukaryotes, where it plays a role in the synthesis of isopentanyl pyrophosphate, a common intermediate for a number of pathways including cholesterol biosynthesis. It is also involved in mevalonate catabolism. Close homologues are found in the Archaea. A bacterial example is found in the Borrelia burgdorferi(Lyme disease spirochete), but is not necessarily the same biosynthetic enzyme.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



1 Child Features

Id Name Short Name Type
IPR022937 Mevalonate kinase, archaeal Mevalonate_kinase_arc Family

5 Contains

Id Name Short Name Type
IPR020568 Ribosomal protein S5 domain 2-type fold Ribosomal_S5_D2-typ_fold Domain
IPR013750 GHMP kinase, C-terminal domain GHMP_kinase_C_dom Domain
IPR006204 GHMP kinase N-terminal domain GHMP_kinase_N_dom Domain
IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Ribosomal_S5_D2-typ_fold_subgr Domain
IPR006203 GHMP kinase, ATP-binding, conserved site GHMP_knse_ATP-bd_CS Conserved_site

0 Found In

1 Parent Features

Id Name Short Name Type
IPR006206 Mevalonate/galactokinase Mevalonate/galactokinase Family

0 Publications

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)