InterPro : IPR018982

Name  RQC domain Short Name  RQC_domain
Type  Domain Description  This entry represents the RQC domain, which is a DNA-binding domain found only in RecQ family enzymes. RecQ family helicases can unwind G4 DNA, and play important roles at G-rich domains of the genome, including the telomeres, rDNA, and immunoglobulin switch regions. This domain has a helix-turn-helix structure and acts as a high affinity G4 DNA binding domain []. Binding of RecQ to Holliday junctions involves both the RQC and the HRDC domains.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

0 Contains

2 Found In

Id Name Short Name Type
IPR004589 DNA helicase, ATP-dependent, RecQ type DNA_helicase_ATP-dep_RecQ Family
IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial DNA_helicase_ATP-dep_RecQ_bac Family

0 Parent Features

1 Publications

First Author Title Year Journal Volume Pages
Huber MD A conserved G4 DNA binding domain in RecQ family helicases. 2006 J Mol Biol 358 1071-80

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)