InterPro : IPR008851

Name  Transcription initiation factor IIF, alpha subunit Short Name  TFIIF-alpha
Type  Family Description  Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) or RNA polymerase II-associating protein 74 (RAP74) is the large subunit of transcription factor IIF (TFIIF), which is essential for accurate initiation and stimulates elongation by RNA polymerase II [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

2 Contains

Id Name Short Name Type
IPR011991 Winged helix-turn-helix DNA-binding domain WHTH_DNA-bd_dom Domain
IPR011039 Transcription Factor IIF, Rap30/Rap74, interaction TFIIF_interaction Domain

0 Found In

0 Parent Features

1 Publications

First Author Title Year Journal Volume Pages
Funk JD A key role for the alpha 1 helix of human RAP74 in the initiation and elongation of RNA chains. 2002 J Biol Chem 277 46998-7003

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)