InterPro : IPR019539

Name  Galactokinase galactose-binding domain Short Name  GalKase_gal-bd
Type  Domain Description  This entry represents a highly conserved galactokinase signature sequence which appears to be present in all galactokinases, irrespective of how many other ATP binding sites, etc that they carry []. The function of this domain appears to be to bind galactose [], and it is normally located at the N terminus of these enzymes []. It is associated with and . While all enzymes in this entry posses galactokinase activity, some are annotated as N-acetylgalactosamine kinases as they also posses this enzyme activity.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

1 Contains

Id Name Short Name Type
IPR019741 Galactokinase, conserved site Galactokinase_CS Conserved_site

4 Found In

Id Name Short Name Type
IPR020568 Ribosomal protein S5 domain 2-type fold Ribosomal_S5_D2-typ_fold Domain
IPR006206 Mevalonate/galactokinase Mevalonate/galactokinase Family
IPR000705 Galactokinase Galactokinase Family
IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Ribosomal_S5_D2-typ_fold_subgr Domain

0 Parent Features

3 Publications

First Author Title Year Journal Volume Pages
Thoden JB Molecular structure of galactokinase. 2003 J Biol Chem 278 33305-11
Schalkwijk J The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide core. 1999 Biochem J 340 ( Pt 3) 569-77
Holden HM Galactokinase: structure, function and role in type II galactosemia. 2004 Cell Mol Life Sci 61 2471-84

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)