InterPro : IPR015412

Name  Autophagy-related, C-terminal Short Name  Autophagy-rel_C
Type  Domain Description  Eukaryotes have developed an evolutionarily conserved process, termed autophagy, to survive starvation conditions. The vacuole or lysosome mediates the turnover and recycling of non-essential intracellular material for re-use in critical biosynthetic reactions. ATG2 (also known as Apg2) is required for the formation and/or completion of cytosolic sequestering vesicles that are needed for vacuolar import through both the Cvt pathway and autophagy, as well as for the specific degradation of peroxisomes. Apg2 is a peripheral membrane protein that localises to the previously identified perivacuolar compartment that contains Apg9 [].This entry represents the C-terminal domain of Apg2 and related proteins.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

0 Contains

1 Found In

Id Name Short Name Type
IPR017148 Vacuolar protein sorting-associated protein 13, fungi VPS13_fungi Family

0 Parent Features

1 Publications

First Author Title Year Journal Volume Pages
Wang CW Apg2 is a novel protein required for the cytoplasm to vacuole targeting, autophagy, and pexophagy pathways. 2001 J Biol Chem 276 30442-51

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)