InterPro : IPR007857

Name  Protein arginine N-methyltransferase PRMT5 Short Name  Arg_MeTrfase_PRMT5
Type  Family Description  The human homologue of Saccharomyces cerevisiaeSkb1 (Shk1 kinase-binding protein 1) is PRMT5, an arginine-N-methyltransferase [, ]. These proteins appear to be key mitotic regulators. They play a role in Jak signalling in higher eukaryotes.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

0 Contains

0 Found In

1 Parent Features

Id Name Short Name Type
IPR025799 Protein arginine N-methyltransferase Arg_MeTrfase Family

2 Publications

First Author Title Year Journal Volume Pages
Pollack BP The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity. 1999 J Biol Chem 274 31531-42
Rho J Prmt5, which forms distinct homo-oligomers, is a member of the protein-arginine methyltransferase family. 2001 J Biol Chem 276 11393-401

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)