InterPro : IPR013684

Name  Mitochondrial Rho-like Short Name  MIRO-like
Type  Domain Description  Mitochondrial Rho proteins (Miro-1, and Miro-2, ) are atypical Rho GTPases. They have a unique domain organisation, with tandem GTP-binding domains and two EF hand domains (), that may bind calcium. They are also larger than classical small GTPases. It has been proposed that they are involved in mitochondrial homeostasis and apoptosis [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



1 Child Features

Id Name Short Name Type
IPR020860 MIRO MIRO Domain

0 Contains

5 Found In

Id Name Short Name Type
IPR001806 Small GTPase superfamily Small_GTPase Family
IPR005225 Small GTP-binding protein domain Small_GTP-bd_dom Domain
IPR020859 ROC GTPase ROC_GTPase Domain
IPR021181 Small GTPase superfamily, mitochondrial Rho Rho_GTPase_Mt Family
IPR017231 Small GTPase superfamily, Tem1 Small_GTPase_Tem1 Family

0 Parent Features

1 Publications

First Author Title Year Journal Volume Pages
Fransson A Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis. 2003 J Biol Chem 278 6495-502

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)