InterPro : IPR024253

Name  Phosducin, thioredoxin-like domain Short Name  Phosducin_thioredoxin-like_dom
Type  Domain Description  The outer and inner segments of vertebrate rod photoreceptor cells contain phosducin,a soluble phosphoprotein that complexes with the beta/gamma-subunits of the GTP-bindingprotein, transducin. Light-induced changes in cyclic nucleotide levels modulate thephosphorylation of phosducin by protein kinase A []. The protein is thought to participate in the regulation ofvisual phototransduction or in the integration of photo-receptor metabolism. Similarproteins have been isolated from the pineal gland and it is believed that the functionalrole of the protein is the same in both retina and pineal gland [].This entry represents a domain found in members of the phosducin family. This domain has a thioredoxin-like fold [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

0 Contains

0 Found In

1 Parent Features

Id Name Short Name Type
IPR012336 Thioredoxin-like fold Thioredoxin-like_fold Domain

3 Publications

First Author Title Year Journal Volume Pages
Abe T Analysis of the human, bovine and rat 33-kDa proteins and cDNA in retina and pineal gland. 1990 Gene 91 209-15
Lee RH Amino acid and cDNA sequence of bovine phosducin, a soluble phosphoprotein from photoreceptor cells. 1990 J Biol Chem 265 15867-73
Lou X Structure of the thioredoxin-fold domain of human phosducin-like protein 2. 2009 Acta Crystallogr Sect F Struct Biol Cryst Commun 65 67-70

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)