InterPro : IPR011038

Name  Calycin-like Short Name  Calycin-like
Type  Domain Description  Calycins form a large protein superfamily that share similar beta-barrel structures. Calycins can be divided into families that include lipocalins, fatty acid binding proteins, triabin, and thrombin inhibitor []. Of these families, the lipocalin family () is the largest and functionally the most diverse. Lipocalins are extracellular proteins that share several common recognition properties such as ligand binding, receptor binding and the formation of complexes with other macromolecules. Lipocalins include the retinol binding protein, lipocalin allergen, aphrodisin (a sex hormone), alpha-2U-globulin, prostaglandin D synthase, beta-lactoglobulin, bilin-binding protein, and the nitrophorins [, , , ]. Bacterial hypothetical proteins YodA from Escherichia coliand YwiB from Bacillus subtilisshare a similar calycin beta-barrel structure. Part of the YodA hypothetical protein has a calycin-like structure [].This entry represents calycin as well as some other proteins that share a similar calycin beta-barrel structure, including UPF0678 fatty acid-binding protein-like proteins [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



1 Child Features

Id Name Short Name Type
IPR012674 Calycin Calycin Domain

1 Contains

Id Name Short Name Type
IPR022272 Lipocalin family conserved site Lipocalin_CS Conserved_site

8 Found In

Id Name Short Name Type
IPR002345 Lipocalin Lipocalin Family
IPR002968 Alpha-1-microglobulin A1-microglobln Family
IPR002969 Apolipoprotein D ApolipopD Family
IPR022271 Lipocalin, ApoD type Lipocalin_ApoD Family
IPR002970 Tick histamine-binding protein Tick_his-bd Family
IPR003057 Invertebrate colouration protein Invtbrt_color Family
IPR022734 Apolipoprotein M ApoM Family
IPR015231 Protein of unknown function DUF1934 DUF1934 Family

0 Parent Features

7 Publications

First Author Title Year Journal Volume Pages
Flower DR The lipocalin protein family: structural and sequence overview. 2000 Biochim Biophys Acta 1482 9-24
Cavaggioni A Major urinary proteins, alpha(2U)-globulins and aphrodisin. 2000 Biochim Biophys Acta 1482 218-28
Lögdberg L Immunocalins: a lipocalin subfamily that modulates immune and inflammatory responses. 2000 Biochim Biophys Acta 1482 284-97
Sawyer L The core lipocalin, bovine beta-lactoglobulin. 2000 Biochim Biophys Acta 1482 136-48
Urade Y Lipocalin-type and hematopoietic prostaglandin D synthases as a novel example of functional convergence. 2002 Prostaglandins Other Lipid Mediat 68-69 375-82
David G YodA from Escherichia coli is a metal-binding, lipocalin-like protein. 2003 J Biol Chem 278 43728-35
Bianchetti CM The structure and NO binding properties of the nitrophorin-like heme-binding protein from Arabidopsis thaliana gene locus At1g79260.1. 2010 Proteins 78 917-31

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)