InterPro : IPR015878

Name  S-adenosyl-L-homocysteine hydrolase, NAD binding domain Short Name  Ado_hCys_hydrolase_NAD-bd
Type  Domain Description  S-adenosyl-L-homocysteine hydrolase () (AdoHcyase) is an enzyme of the activated methyl cycle, responsible for the reversible hydration of S-adenosyl-L-homocysteine into adenosine and homocysteine. AdoHcyase is an ubiquitous enzyme which binds and requires NAD+as a cofactor.AdoHcyase is a highly conserved protein []of about 430 to 470 amino acids. This entry represents the glycine-rich region in the central part of AdoHcyase, which is thought to be involved in NAD-binding [].
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Sequence Features

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Proteins

InterPro protein domain ID --> Contigs

 

Other

0 Child Features

1 Contains

Id Name Short Name Type
IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site S-Ado-L-homoCys_hydrolase_CS Conserved_site

1 Found In

Id Name Short Name Type
IPR000043 Adenosylhomocysteinase Adenosylhomocysteinase Family

0 Parent Features

1 Publications

First Author Title Year Journal Volume Pages
Sganga MW Mutational and nucleotide sequence analysis of S-adenosyl-L-homocysteine hydrolase from Rhodobacter capsulatus. 1992 Proc Natl Acad Sci U S A 89 6328-32



To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)