InterPro : IPR000043

Name  Adenosylhomocysteinase Short Name  Adenosylhomocysteinase
Type  Family Description  Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase, ) (AdoHcyase) is an enzyme of the activated methyl cycle, responsible for the reversible hydration of S-adenosyl-L-homocysteine into adenosine and homocysteine. This enzyme is ubiquitous, highly conserved, and may play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. AdoHcyase requires NAD+as a cofactor and contains a central glycine-rich region which is thought to be involved in NAD-binding.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

2 Contains

Id Name Short Name Type
IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ado_hCys_hydrolase_NAD-bd Domain
IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site S-Ado-L-homoCys_hydrolase_CS Conserved_site

0 Found In

0 Parent Features

0 Publications

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)