InterPro : IPR006076

Name  FAD dependent oxidoreductase Short Name  FAD-dep_OxRdtase
Type  Domain Description  This entry includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase (), Sarcosine oxidase beta subunit (), D-alanine oxidase (), D-aspartate oxidase (). D-amino acid oxidase () (DAMOX or DAO) is an FAD flavoenzyme that catalyzes the oxidation of neutral and basic D-amino acids into their corresponding keto acids. DAOs have been characterised and sequenced in fungi and vertebrates where they are known to be located in the peroxisomes. D-aspartate oxidase () (DASOX) []is an enzyme, structurally related to DAO, which catalyzes the same reaction but is active only toward dicarboxylic D-amino acids. In DAO, a conserved histidine has been shown []to be important for the enzyme's catalytic activity.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



1 Child Features

Id Name Short Name Type
IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal tRNA_S-uridine_synth_MnmC_C Domain

1 Contains

Id Name Short Name Type
IPR006181 D-amino acid oxidase, conserved site D-amino_acid_oxidase_CS Conserved_site

13 Found In

Id Name Short Name Type
IPR010971 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/UbiI/COQ6 Ubi_Hdrxlases Family
IPR015657 Aminobutyraldehyde dehydrogenase Aminobutyraldehyde_DH Family
IPR004379 UDP-galactopyranose mutase UDP-GALP_mutase Family
IPR014104 Myxoxanthophyll biosynthesis, C-3',4' desaturase CrtD Myxoxanthophyll_desat_CrtD Family
IPR014101 Carotene isomerase Carotene_isomerase Family
IPR012727 Glycine oxidase ThiO Gly_oxidase_ThiO Family
IPR011295 2-polyprenyl-6-methoxyphenol 4-hydroxylase UbiH Family
IPR017631 Salicylate 1-monooxygenase Salicylate_mOase Family
IPR017715 Putative aminophosphonate oxidoreductase NH2-phosphonate_OxRdtase Family
IPR017741 FAD-dependent oxidoreductase, HpnW FAD-dependent_OxRdtase_HpnW Family
IPR023080 D-amino acid dehydrogenase small subunit, DadA D-aa_DH_ssu_DadA Family
IPR006278 Sarcosine oxidase, beta subunit, heterotetrameric SoxB Family
IPR006281 Sarcosine oxidase, monomeric SoxA_mon Family

0 Parent Features

2 Publications

First Author Title Year Journal Volume Pages
Miyano M Studies on Phe-228 and Leu-307 recombinant mutants of porcine kidney D-amino acid oxidase: expression, purification, and characterization. 1991 J Biochem 109 171-7
Negri A The primary structure of the flavoprotein D-aspartate oxidase from beef kidney. 1992 J Biol Chem 267 11865-71

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)