InterPro : IPR017340

Name  U1 small nuclear ribonucleoprotein C Short Name  U1_snRNP-C
Type  Family Description  This group represents U1 small nuclear ribonucleoprotein C. It is a component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA [, , ].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

2 Contains

Id Name Short Name Type
IPR013085 Zinc finger, U1-C type Znf_U1-C Domain
IPR000690 Zinc finger, C2H2-type matrin Znf_C2H2_matrin Domain

0 Found In

0 Parent Features

3 Publications

First Author Title Year Journal Volume Pages
Rossi F Involvement of U1 small nuclear ribonucleoproteins (snRNP) in 5' splice site-U1 snRNP interaction. 1996 J Biol Chem 271 23985-91
Heinrichs V U1-specific protein C needed for efficient complex formation of U1 snRNP with a 5' splice site. 1990 Science 247 69-72
Nelissen RL Zinc finger-like structure in U1-specific protein C is essential for specific binding to U1 snRNP. 1991 Nucleic Acids Res 19 449-54

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)