InterPro : IPR023566

Name  Peptidyl-prolyl cis-trans isomerase, FKBP-type Short Name  PPIase_FKBP
Type  Family Description  Synonym(s): Peptidylprolyl cis-trans isomeraseFKBP-type peptidylprolyl isomerases () in vertebrates, are receptors for the two immunosuppressants, FK506 and rapamycin. The drugs inhibit T cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. Peptidylprolyl isomerases accelerate protein folding by catalysing the cis-trans isomerisation of proline imidic peptide bonds in oligopeptides. These proteins are found in a variety of organisms.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



2 Child Features

Id Name Short Name Type
IPR026257 FK506-binding protein FK506_BP Family
IPR008104 Macrophage infectivity potentiator INFPOTNTIATR Family

0 Contains

0 Found In

0 Parent Features

0 Publications

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)