InterPro : IPR001357

Name  BRCT domain Short Name  BRCT_dom
Type  Domain Description  The BRCT domain (after the C_terminal domain of a breast cancer susceptibility protein) is found predominantly in proteins involved in cell cycle checkpoint functions responsive to DNA damage [], for example as found in the breast cancer DNA-repair protein BRCA1. The domain is an approximately 100 amino acid tandem repeat, which appears to act as a phospho-protein binding domain [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

0 Contains

8 Found In

Id Name Short Name Type
IPR012112 DNA repair protein, Rev1 REV1 Family
IPR008288 NAD+ ADP-ribosyltransferase NAD_ADPRT Family
IPR011364 Breast cancer type 1 susceptibility protein (BRCA1) BRCA1 Family
IPR001679 NAD-dependent DNA ligase DNAligase Family
IPR022312 DNA polymerase family X DNA_pol_X Family
IPR001726 DNA nucleotidylexotransferase (TdT) / DNA-directed DNA/RNA polymerase mu TdT/Mu Family
IPR016592 Nibrin Nibrin_met Family
IPR012178 DNA replication factor C, large subunit DNA_replication_fac_C_lsu Family

0 Parent Features

2 Publications

First Author Title Year Journal Volume Pages
Bork P A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins. 1997 FASEB J 11 68-76
Yu X The BRCT domain is a phospho-protein binding domain. 2003 Science 302 639-42

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)