InterPro : IPR008409

Name  Pre-mRNA-splicing factor SPF27 Short Name  SPF27
Type  Family Description  Proteins in this family are involved in mRNA splicing []. This family includes pre-mRNA-splicing factor SPF27, SNT309 and Cwf7. In humans, SPF27 is a component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. It may have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

0 Contains

0 Found In

0 Parent Features

2 Publications

First Author Title Year Journal Volume Pages
Palma K Regulation of plant innate immunity by three proteins in a complex conserved across the plant and animal kingdoms. 2007 Genes Dev 21 1484-93
Grote M Molecular architecture of the human Prp19/CDC5L complex. 2010 Mol Cell Biol 30 2105-19

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)