InterPro : IPR012677

Name  Nucleotide-binding alpha-beta plait domain Short Name  Nucleotide-bd_a/b_plait
Type  Domain Description  This entry represents nucleotide-binding domains with an alpha-beta plait structure, which consists of either a ferredoxin-like (beta-alpha-beta)2 fold, such as that found in RNA-binding domains of various ribonucleoproteins or in viral DNA-binding domains [, ]; or a beta-(alpha)-beta-alpha-beta(2) fold, such as that found in the ribosomal protein L23 [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



4 Child Features

Id Name Short Name Type
IPR000504 RNA recognition motif domain RRM_dom Domain
IPR012678 Ribosomal protein L23/L15e core domain Ribosomal_L23/L15e_core_dom Domain
IPR014789 Poly(A)-specific ribonuclease, RNA-binding PolyA-riboNase_RNA_binding Domain
IPR015245 Nuclear RNA export factor Tap, RNA-binding domain Tap_RNA-bd Domain

4 Contains

Id Name Short Name Type
IPR000504 RNA recognition motif domain RRM_dom Domain
IPR014886 RNA-binding motif RRM_3 Domain
IPR018098 Ribosomal S24e conserved site Ribosomal_S24e_CS Conserved_site
IPR001014 Ribosomal protein L23/L25, conserved site Ribosomal_L23/L25_CS Conserved_site

10 Found In

Id Name Short Name Type
IPR017334 Eukaryotic translation initiation factor 3 subunit G eIF3_g Family
IPR005120 Regulator of nonsense-mediated decay, UPF3 Nonsense_mediated_decay_UPF3 Domain
IPR013025 Ribosomal protein L25/L23 Ribosomal_L25/23 Family
IPR019985 Ribosomal protein L23 Ribosomal_L23 Family
IPR006509 Splicing factor, RBM39-like RBM39_SF Family
IPR016304 Cyclophilin-type peptidyl-prolyl cis-trans isomerase E Cyclophilin-type_PPIase_E Family
IPR016967 Splicing factor, SPF45 Splicing_factor_SPF45 Family
IPR017325 RNA binding protein Fox-1 RNA-bd_Fox-1 Family
IPR017347 Heterogeneous nuclear ribonucleoprotein C, Raly hnRNP_C_Raly Family
IPR000427 Papillomavirus E2, C-terminal Papillomavirus_E2_C Domain

0 Parent Features

3 Publications

First Author Title Year Journal Volume Pages
Kielkopf CL U2AF homology motifs: protein recognition in the RRM world. 2004 Genes Dev 18 1513-26
Bochkarev A Crystal structure of the DNA-binding domain of the Epstein-Barr virus origin-binding protein EBNA 1. 1995 Cell 83 39-46
Chenuil A Evolution of the large-subunit ribosomal RNA binding site for protein L23/25. 1997 Mol Biol Evol 14 578-88

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)