Author :

Name  Fahey RC
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13 Publications

First Author Title Year Journal Volume Pages
Maynes JT The crystal structure of 1-D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis reveals a zinc hydrolase with a lactate dehydrogenase fold. 2003 J Biol Chem 278 47166-70
Newton GL N-Acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) is a key enzyme in mycothiol biosynthesis. 2000 J Bacteriol 182 6958-63
Newton GL Distribution of thiols in microorganisms: mycothiol is a major thiol in most actinomycetes. 1996 J Bacteriol 178 1990-5
Newton GL Purification and characterization of Mycobacterium tuberculosis 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, MshB, a mycothiol biosynthetic enzyme. 2006 Protein Expr Purif 47 542-50
Steffek M Characterization of Mycobacterium tuberculosis mycothiol S-conjugate amidase. 2003 Biochemistry 42 12067-76
Newton GL A coupled spectrophotometric assay for l-cysteine:1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase and its application for inhibitor screening. 2006 Anal Biochem 353 167-73
Sareen D Mycothiol is essential for growth of Mycobacterium tuberculosis Erdman. 2003 J Bacteriol 185 6736-40
Fahey RC Novel thiols of prokaryotes. 2001 Annu Rev Microbiol 55 333-56
Rawat M Mycothiol-deficient Mycobacterium smegmatis mutants are hypersensitive to alkylating agents, free radicals, and antibiotics. 2002 Antimicrob Agents Chemother 46 3348-55
Koledin T Identification of the mycothiol synthase gene (mshD) encoding the acetyltransferase producing mycothiol in actinomycetes. 2002 Arch Microbiol 178 331-7
Newton GL Biochemistry of the initial steps of mycothiol biosynthesis. 2006 J Biol Chem 281 33910-20
Gaballa A Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli. 2010 Proc Natl Acad Sci U S A 107 6482-6
Sareen D ATP-dependent L-cysteine:1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, mycothiol biosynthesis enzyme MshC, is related to class I cysteinyl-tRNA synthetases. 2002 Biochemistry 41 6885-90



To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)