Author :

Name  Wittinghofer A

29 Publications

First Author Title Year Journal Volume Pages
Rudolph MG The Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein (WASP) is necessary but not sufficient for tight binding to Cdc42 and structure formation. 1998 J Biol Chem 273 18067-76
Vetter IR Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport. 1999 Nature 398 39-46
Shimada A The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization. 2004 Mol Cell 13 511-22
Vetter IR Structural view of the Ran-Importin beta interaction at 2.3 A resolution. 1999 Cell 97 635-46
Valencia A The ras protein family: evolutionary tree and role of conserved amino acids. 1991 Biochemistry 30 4637-48
Pai EF Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis. 1990 EMBO J 9 2351-9
Scheffzek K Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form. 1995 Nature 374 378-81
Saraste M The P-loop--a common motif in ATP- and GTP-binding proteins. 1990 Trends Biochem Sci 15 430-4
Koller-Eichhorn R Human OLA1 defines an ATPase subfamily in the Obg family of GTP-binding proteins. 2007 J Biol Chem 282 19928-37
Rossbach M Crystal structure of THEP1 from the hyperthermophile Aquifex aeolicus: a variation of the RecA fold. 2005 BMC Struct Biol 5 7
Thomas C Structural evidence for a common intermediate in small G protein-GEF reactions. 2007 Mol Cell 25 141-9
Berken A A new family of RhoGEFs activates the Rop molecular switch in plants. 2005 Nature 436 1176-80
Thomas C Purification and crystallization of the catalytic PRONE domain of RopGEF8 and its complex with Rop4 from Arabidopsis thaliana. 2006 Acta Crystallogr Sect F Struct Biol Cryst Commun 62 607-10
Hanzal-Bayer M The complex of Arl2-GTP and PDE delta: from structure to function. 2002 EMBO J 21 2095-106
Veltel S The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3. 2008 Nat Struct Mol Biol 15 373-80
Lammers M The regulation of mDia1 by autoinhibition and its release by Rho*GTP. 2005 EMBO J 24 4176-87
Rose R Structural and mechanistic insights into the interaction between Rho and mammalian Dia. 2005 Nature 435 513-8
Kühnel K The VASP tetramerization domain is a right-handed coiled coil based on a 15-residue repeat. 2004 Proc Natl Acad Sci U S A 101 17027-32
Buchwald G Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE. 2002 EMBO J 21 3286-95
Farkasovsky M Nucleotide binding and filament assembly of recombinant yeast septin complexes. 2005 Biol Chem 386 643-56
Kühnel K Crystal structure of the human retinitis pigmentosa 2 protein and its interaction with Arl3. 2006 Structure 14 367-78
Scrima A The structure of the TrmE GTP-binding protein and its implications for tRNA modification. 2005 EMBO J 24 23-33
Meyer S Crystal structures of the conserved tRNA-modifying enzyme GidA: implications for its interaction with MnmE and substrate. 2008 J Mol Biol 380 532-47
Nassar N The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue. 1995 Nature 375 554-60
Scheffzek K The Ras-Byr2RBD complex: structural basis for Ras effector recognition in yeast. 2001 Structure 9 1043-50
Sirajuddin M Structural insight into filament formation by mammalian septins. 2007 Nature 449 311-5
Prakash B Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins. 2000 Nature 403 567-71
Prakash B Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism. 2000 EMBO J 19 4555-64
Ghosh A How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP. 2006 Nature 440 101-4

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)