InterPro : IPR001808

Name  Transcription regulator HTH, Crp Short Name  Tscrpt_reg_HTH_Crp
Type  Domain Description  Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. This family groups together a range of proteins, including anr, crp, clp, cysR, fixK, flp, fnr, fnrN, hlyX and ntcA [, ]. Within this family, the HTH motif is situated towards the C terminus.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

1 Contains

Id Name Short Name Type
IPR018335 Transcription regulator HTH, Crp-type, conserved site Tscrpt_reg_HTH_Crp-type_CS Conserved_site

2 Found In

Id Name Short Name Type
IPR011991 Winged helix-turn-helix DNA-binding domain WHTH_DNA-bd_dom Domain
IPR022299 Transcription regulator, NtcA Tscrpt_reg_NtcA Family

1 Parent Features

Id Name Short Name Type
IPR012318 Helix-turn-helix motif, Crp-type HTH_CRP_2 Domain

2 Publications

First Author Title Year Journal Volume Pages
Körner H Phylogeny of the bacterial superfamily of Crp-Fnr transcription regulators: exploiting the metabolic spectrum by controlling alternative gene programs. 2003 FEMS Microbiol Rev 27 559-92
Busby S Transcription activation by catabolite activator protein (CAP). 1999 J Mol Biol 293 199-213

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)