InterPro : IPR018457

Name  LacY/RafB permease family, conserved site Short Name  LacY/RafB_perm_fam_CS
Type  Conserved_site Description  In bacteria there are a number of families of transport proteins, including symporters and antiporters, thatmediate the intake of a variety of sugars with the concomitant uptake of hydrogen ions (proton symporters)[]. The lacY family of Escherichia coliand Klebsiella pneumoniaeare proton/beta-galactoside symporters,which, like most sugar transporters, are integral membrane proteins with 12 predicted transmembrane (TM) regions.Also similar to the lacY family are the rafinose (rafB) and sucrose (cscB) permeases from E. coli [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

0 Contains

2 Found In

Id Name Short Name Type
IPR020846 Major facilitator superfamily domain MFS_dom Domain
IPR000576 LacY/RafB permease family LacY/RafB_perm_fam Family

0 Parent Features

2 Publications

First Author Title Year Journal Volume Pages
Bockmann J Characterization of a chromosomally encoded, non-PTS metabolic pathway for sucrose utilization in Escherichia coli EC3132. 1992 Mol Gen Genet 235 22-32
Marger MD A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport. 1993 Trends Biochem Sci 18 13-20

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)