InterPro : IPR005546

Name  Autotransporter beta-domain Short Name  Auto_transptbeta
Type  Domain Description  Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease []. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs []. In those proteins where thecleavage is auto-catalytic, the peptidase domains belong to MEROPS peptidase families S6 and S8.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

0 Contains

6 Found In

Id Name Short Name Type
IPR016955 Autotransporter, YhjY, predicted Autotranspt_YhjY_prd Family
IPR003991 Pertactin virulence factor family Pertactin_virulence_factor Family
IPR003992 Pertactin Pertactin Family
IPR006315 Outer membrane autotransporter barrel OM_autotransptr_brl Domain
IPR017318 Peptidase S8A, subtilisin-related, campylobacter Pept_S8A_subtilisin_campylobac Family
IPR017186 Lipase, autotransporter EstA Lipase_autotranspt_EstA Family

0 Parent Features

2 Publications

First Author Title Year Journal Volume Pages
Pohlner J Gene structure and extracellular secretion of Neisseria gonorrhoeae IgA protease. 1987 Nature 325 458-62
Henderson IR The great escape: structure and function of the autotransporter proteins. 1998 Trends Microbiol 6 370-8

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)