InterPro : IPR027513

Name  tRNA-splicing ligase RtcB homologue, eukaryotic Short Name  RtcB_euk
Type  Family Description  RctB is a tRNA-splicing ligase from bacteria []. RctB homologues in eukaryotes represent the catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. RctB may act as a RNA ligase with broad substrate specificity, and may function toward other RNAs [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

0 Contains

0 Found In

1 Parent Features

Id Name Short Name Type
IPR001233 tRNA-splicing ligase, RtcB RtcB Family

2 Publications

First Author Title Year Journal Volume Pages
Tanaka N RtcB is the RNA ligase component of an Escherichia coli RNA repair operon. 2011 J Biol Chem 286 7727-31
Popow J HSPC117 is the essential subunit of a human tRNA splicing ligase complex. 2011 Science 331 760-4

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)