InterPro : IPR003054

Name  Keratin, type II Short Name  Keratin_II
Type  Family Description  Intermediate filaments (IF) [, , ]are proteins which are primordial components of the cytoskeleton and the nuclear envelope. They generally form filamentous structures 8 to 14 nm wide.Type II keratins are the basic or neutral courterparts to the acidic type Ikeratins. Each type II keratin forms a heterodimer with a specific acidickeratin, and the heterodimers are organised into tetramers and then intochains []. Type II keratins consist of head-, rod- and tail-likestructures, the rod being constructed from three linked coils: 1A, 1B and 2.The head and tail structures of the type 2 keratins are highly variablelow-complexity regions.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

1 Contains

Id Name Short Name Type
IPR018039 Intermediate filament protein, conserved site Intermediate_filament_CS Conserved_site

0 Found In

1 Parent Features

Id Name Short Name Type
IPR001664 Intermediate filament protein IF Family

3 Publications

First Author Title Year Journal Volume Pages
Quinlan R Intermediate filament proteins. 1995 Protein Profile 2 795-952
Steinert PM Molecular and cellular biology of intermediate filaments. 1988 Annu Rev Biochem 57 593-625
Stewart M Intermediate filaments: structure, assembly and molecular interactions. 1990 Curr Opin Cell Biol 2 91-100

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)