InterPro : IPR011295

Name  2-polyprenyl-6-methoxyphenol 4-hydroxylase Short Name  UbiH
Type  Family Description  This entry represents the FAD-dependent monooxygenase responsible for the second hydroxylation step in the aerobic ubiquinone biosynthetic pathway [, , ]. The sequences in this entry are restricted to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyses the final hydroxylation step. The enzyme has also been named VisB due to a mutant visible light sensitive phenotype.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

2 Contains

Id Name Short Name Type
IPR006076 FAD dependent oxidoreductase FAD-dep_OxRdtase Domain
IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site Ubi_Hdrlase_CS Conserved_site

0 Found In

1 Parent Features

Id Name Short Name Type
IPR010971 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/UbiI/COQ6 Ubi_Hdrxlases Family

3 Publications

First Author Title Year Journal Volume Pages
Meganathan R Ubiquinone biosynthesis in microorganisms. 2001 FEMS Microbiol Lett 203 131-9
Nakahigashi K Isolation and characterization of a light-sensitive mutant of Escherichia coli K-12 with a mutation in a gene that is required for the biosynthesis of ubiquinone. 1992 J Bacteriol 174 7352-9
Young IG Pathway for ubiquinone biosynthesis in Escherichia coli K-12: gene-enzyme relationships and intermediates. 1973 J Bacteriol 114 42-52

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)