InterPro : IPR017050

Name  Metallopeptidase, nematode Short Name  Metallopeptidase_nem
Type  Family Description  This family of metallopeptidases is found in nematodes and belongs to the wider peptidase M12A family. Mutant studies and RNAi analyses suggest that the family has an important role in the moulting process [, ]. The proteases are thought to be secreted by hypodermal cells and to participate in shedding of old cuticles.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

4 Contains

Id Name Short Name Type
IPR013032 EGF-like, conserved site EGF-like_CS Conserved_site
IPR000859 CUB domain CUB_dom Domain
IPR001506 Peptidase M12A, astacin Peptidase_M12A Domain
IPR006026 Peptidase, metallopeptidase Peptidase_Metallo Domain

0 Found In

0 Parent Features

2 Publications

First Author Title Year Journal Volume Pages
Suzuki M Metalloproteases with EGF, CUB, and thrombospondin-1 domains function in molting of Caenorhabditis elegans. 2004 Biol Chem 385 565-8
Davis MW A conserved metalloprotease mediates ecdysis in Caenorhabditis elegans. 2004 Development 131 6001-8

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)