InterPro : IPR017310

Name  Peptidase S8A, subtilisin-related, clostridia Short Name  Pept_S8A_subtilisin_clostridia
Type  Family Description  This entry contains serine peptidases belonging to MEROPS peptidase family S8A (subtilisin family, clan SB), which include unassigned and non-peptidase homologues related to the peptidase CspB from Clostridium perfringens. The CspA, CspB and CspC gene products are encoded by genes that are immediately upstream of two cortex lytic enzymes: SleC and SleM. CspA, CspB and CspC are germination specific peptidases that are required for the maturation of SleC and SleM. CspC has a secretion signal unlike CspA and CspB suggesting that they have different subcellular locations. The csp genes and sleM and sleC are conserved among many of the clostridia and are synthesized during stage II-III of sporulation [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

2 Contains

Id Name Short Name Type
IPR000209 Peptidase S8/S53 domain Peptidase_S8/S53_dom Domain
IPR022398 Peptidase S8, subtilisin, His-active site Peptidase_S8_His-AS Active_site

0 Found In

1 Parent Features

Id Name Short Name Type
IPR015500 Peptidase S8, subtilisin-related Peptidase_S8_subtilisin-rel Family

1 Publications

First Author Title Year Journal Volume Pages
Masayama A Expression of germination-related enzymes, CspA, CspB, CspC, SleC, and SleM, of Clostridium perfringens S40 in the mother cell compartment of sporulating cells. 2006 Genes Genet Syst 81 227-34

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)