InterPro : IPR010076

Name  Pimelyl-[acyl-carrier protein]methyl ester esterase Short Name  BioH
Type  Family Description  This CoA-binding enzyme is required for the production of pimeloyl-coenzyme A, the substrate of the BioF protein early in the biosynthesis of biotin []. Its exact function is unknown, but it has been shown to possess carboxylesterase activity with a preference for short acyl chain substrates []. This enzyme belongs to the alpha/beta hydrolase fold family. Members of this family are restricted to the Proteobacteria.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

1 Contains

Id Name Short Name Type
IPR000073 Alpha/beta hydrolase fold-1 AB_hydrolase_1 Domain

0 Found In

0 Parent Features

2 Publications

First Author Title Year Journal Volume Pages
Tomczyk NH Purification and characterisation of the BIOH protein from the biotin biosynthetic pathway. 2002 FEBS Lett 513 299-304
Sanishvili R Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli. 2003 J Biol Chem 278 26039-45

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)