InterPro : IPR022426

Name  Flagellum-specific ATP synthase FliI, clade 3 Short Name  FliI_clade3
Type  Family Description  This family represent the bacterial flagellum-specific ATP synthase, FliI, which is needed for flagellar assembly. FliI is part of the flagellar type III protein export apparatus acting as an ATPase to drive protein export for flagellar biosynthesis [, , ]. When FliI is not engaged in flagellar protein export, FliH, another flagellar type III protein export apparatus protein, functions as a negative regulator to prevent FliI from hydrolysing ATP []. It has been suggested that the N terminus of FliI interacts with FliH, while the the C-terminal domain of FliI possesses the ATPase catalytic function [, ]. The structure of the N-terminally truncated variant of FliI lacking the first 18 residues have been determinded [].This entry represents one (of three) segment of the FliI family tree.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

2 Contains

Id Name Short Name Type
IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain ATPase_F1/V1/A1_a/bsu_nucl-bd Domain
IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site ATPase_a/bsu_AS Active_site

0 Found In

1 Parent Features

Id Name Short Name Type
IPR005714 ATPase, type III secretion system, FliI/YscN ATPase_T3SS_FliI/YscN Family

7 Publications

First Author Title Year Journal Volume Pages
Minamino T Crystallization and preliminary X-ray analysis of Salmonella FliI, the ATPase component of the type III flagellar protein-export apparatus. 2006 Acta Crystallogr Sect F Struct Biol Cryst Commun 62 973-5
Fan F Enzymatic characterization of FliI. An ATPase involved in flagellar assembly in Salmonella typhimurium. 1996 J Biol Chem 271 31981-8
Minamino T FliH, a soluble component of the type III flagellar export apparatus of Salmonella, forms a complex with FliI and inhibits its ATPase activity. 2000 Mol Microbiol 37 1494-503
Minamino T Roles of the extreme N-terminal region of FliH for efficient localization of the FliH-FliI complex to the bacterial flagellar type III export apparatus. 2009 Mol Microbiol 74 1471-83
González-Pedrajo B Molecular dissection of Salmonella FliH, a regulator of the ATPase FliI and the type III flagellar protein export pathway. 2002 Mol Microbiol 45 967-82
Stephens C Identification of the fliI and fliJ components of the Caulobacter flagellar type III protein secretion system. 1997 J Bacteriol 179 5355-65
Jenks PJ A flagellar-specific ATPase (FliI) is necessary for flagellar export in Helicobacter pylori. 1997 FEMS Microbiol Lett 152 205-11

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)