InterPro : IPR017622

Name  Transcription regulator, P21/BotR , Clostridium toxin-associated Short Name  Tscrpt_reg_p21/BotR
Type  Family Description  Regulatory sigma-70 protein, BotR transcription regulator regulates neurotoxin production in Clostridium botulinum. Similarly, tetanus toxin production of Clostridium tetaniis regulated by TetR which is a very close relative of BotR. Functional complementation experiments have been done for botR and tetR in highly transformable strain of Clostridium perfringenshost cells to assess functional interchangeability of sigma factors and it has been confirmed that they are interchangeable in vivo [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

2 Contains

Id Name Short Name Type
IPR013249 RNA polymerase sigma factor 70, region 4 type 2 RNA_pol_sigma70_r4_t2 Domain
IPR014284 RNA polymerase sigma-70 like domain RNA_pol_sigma-70_dom Domain

0 Found In

0 Parent Features

1 Publications

First Author Title Year Journal Volume Pages
Dupuy B Regulation of toxin and bacteriocin gene expression in Clostridium by interchangeable RNA polymerase sigma factors. 2006 Mol Microbiol 60 1044-57

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)