InterPro : IPR005216

Name  Citrate lyase ligase Short Name  Citrate_lyase_ligase
Type  Family Description  [Citrate (pro-3S)-lyase]ligase (), also known as citrate lyase ligase, is responsible for acetylation of the prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase. It converts the inactive thiol form of the enzyme to the active form. In Clostridium sphenoides, citrate lyase ligase actively degrades citrate. In Clostridium sporosphaeroidesand Lactococcus lactis, however, the enzyme is under stringent regulatory control. The enzyme's activity in anaerobic bacteria is modulated by phosphorylation and dephosphorylation [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

3 Contains

Id Name Short Name Type
IPR000182 GNAT domain GNAT_dom Domain
IPR004821 Cytidyltransferase-like domain Cyt_trans-like Domain
IPR013166 Citrate lyase ligase, C-terminal Citrate_lyase_ligase_C Domain

0 Found In

0 Parent Features

1 Publications

First Author Title Year Journal Volume Pages
Antranikian G Covalent modification of citrate lyase ligase from Clostridium sphenoides by phosphorylation/dephosphorylation. 1985 Eur J Biochem 153 413-20

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)