InterPro : IPR017151

Name  5'-3' exoribonuclease 2 Short Name  5_3_exoribonuclease_2
Type  Family Description  5'-3'-exoribonucleases are enzymes that degrade RNA by removing terminal nucleotides from the 5' end. Hydrolytic exoribonucleases, to which this entry belongs, produce nucleotide monosphosphates. An exosome and a 5'-3'-exoribonuclease are important in the degradation of very unstable transcripts [].5'-3' exoribonuclease type 2 (Xrn2, also known as Rat1) occurs in animal, plant and fungal lineages. In Saccharomyces cerevisiae, Rat1 serves to terminateRNA polymerase II (RNAPII) molecules engaged in the production of uncapped RNA [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

2 Contains

Id Name Short Name Type
IPR001878 Zinc finger, CCHC-type Znf_CCHC Domain
IPR004859 Putative 5-3 exonuclease Put_53exo Domain

0 Found In

1 Parent Features

Id Name Short Name Type
IPR027073 5'-3' exoribonuclease 5_3_exoribonuclease Family

2 Publications

First Author Title Year Journal Volume Pages
Clayton C Control of mRNA degradation in trypanosomes. 2008 Biochem Soc Trans 36 520-1
Jimeno-González S The yeast 5'-3' exonuclease Rat1p functions during transcription elongation by RNA polymerase II. 2010 Mol Cell 37 580-7

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)