InterPro : IPR004812

Name  Drug resistance transporter Bcr/CmlA subfamily Short Name  Efflux_drug-R_Bcr/CmlA
Type  Family Description  The drug resistance transporter Bcr/CflA proteins are predicted to have 12 membrane-spanning regions. Members with known activity include Bcr (bicyclomycin resistance protein) in Escherichia coli [], Flor (chloramphenicol and florfenicol resistance) in Salmonella typhimurium [], and CmlA (chloramphenicol resistance) found on the Pseudomonas plasmid R1033 [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

0 Contains

0 Found In

1 Parent Features

Id Name Short Name Type
IPR011701 Major facilitator superfamily MFS Family

3 Publications

First Author Title Year Journal Volume Pages
Bentley J Cloning and sequence analysis of an Escherichia coli gene conferring bicyclomycin resistance. 1993 Gene 127 117-20
Bissonnette L Characterization of the nonenzymatic chloramphenicol resistance (cmlA) gene of the In4 integron of Tn1696: similarity of the product to transmembrane transport proteins. 1991 J Bacteriol 173 4493-502
Braibant M Structural and functional study of the phenicol-specific efflux pump FloR belonging to the major facilitator superfamily. 2005 Antimicrob Agents Chemother 49 2965-71

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)