InterPro : IPR014394

Name  Coagulation factor XIIa/hepatocyte growth factor activator Short Name  Coagulation_fac_XIIa/HGFA
Type  Family Description  This entry represents coagulation factor XII/hepatocyte growth factor activator (HGFA). The proteins contain a C-terminal serine peptidase domain that belongs to MEROPS peptidase family S1A (clan PA(S)) [, ].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

7 Contains

Id Name Short Name Type
IPR013032 EGF-like, conserved site EGF-like_CS Conserved_site
IPR000562 Fibronectin, type II, collagen-binding FN_type2_col-bd Domain
IPR000742 Epidermal growth factor-like domain EG-like_dom Domain
IPR000001 Kringle Kringle Domain
IPR018056 Kringle, conserved site Kringle_CS Conserved_site
IPR018114 Peptidase S1, trypsin family, active site Peptidase_S1_AS Active_site
IPR000083 Fibronectin, type I Fibronectin_type1 Domain

0 Found In

1 Parent Features

Id Name Short Name Type
IPR001314 Peptidase S1A, chymotrypsin-type Peptidase_S1A Family

2 Publications

First Author Title Year Journal Volume Pages
Gonias SL Factor XII bridges coagulation and fibrinolysis again. 2010 Blood 115 4979-80
Schmaier AH Why do we want to know how factor XII levels are modulated? 2010 Thromb Res 125 105-6

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)