InterPro : IPR028791

Name  Calpain-10 Short Name  CAPN10
Type  Family Description  Calpain-10 (CAPN10) is identified as a susceptibility gene of type 2 diabetes mellitus (T2DM), which is characterised by defects in haepatic glucose production, insulin action and insulin secretion []. It may play a role in insulin-stimulated glucose uptake [].
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Sequence Features

GO Displayer

Proteins

InterPro protein domain ID --> Contigs

 

Other

0 Child Features

0 Contains

0 Found In

1 Parent Features

Id Name Short Name Type
IPR022684 Peptidase C2, calpain family Calpain_cysteine_protease Family

2 Publications

First Author Title Year Journal Volume Pages
Brown AE Targeted suppression of calpain-10 expression impairs insulin-stimulated glucose uptake in cultured primary human skeletal muscle cells. 2007 Mol Genet Metab 91 318-24
Ridderstråle M Type 2 diabetes candidate gene CAPN10: first, but not last. 2008 Curr Hypertens Rep 10 19-24



To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)