InterPro : IPR027533

Name  Very-long-chain 3-oxoacyl-CoA reductase, fungal Short Name  3_ketoreductase_fungal
Type  Family Description  Very-long-chain 3-oxoacyl-CoA reductase () is a component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. It catalyses the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids [, , ].
 Feedback

Sequence Features

GO Displayer

Proteins

InterPro protein domain ID --> Contigs

 

Other

0 Child Features

0 Contains

0 Found In

1 Parent Features

Id Name Short Name Type
IPR002198 Short-chain dehydrogenase/reductase SDR DH_sc/Rdtase_SDR Family

3 Publications

First Author Title Year Journal Volume Pages
Beaudoin F A Saccharomyces cerevisiae gene required for heterologous fatty acid elongase activity encodes a microsomal beta-keto-reductase. 2002 J Biol Chem 277 11481-8
Han G The Saccharomyces cerevisiae YBR159w gene encodes the 3-ketoreductase of the microsomal fatty acid elongase. 2002 J Biol Chem 277 35440-9
Rössler H Functional differentiation and selective inactivation of multiple Saccharomyces cerevisiae genes involved in very-long-chain fatty acid synthesis. 2003 Mol Genet Genomics 269 290-8



To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)