InterPro : IPR004746

Name  Major facilitator superfamily, aromatic acid:H+ symporter family Short Name  MFS_AAHS
Type  Family Description  The aromatic acid:H+ symporter family (AAHS) is classified as family 15 of the major facilitator superfamily (MFS) []. Members of the AAHS family show fairly uniform sizes (418 to 460 residues). They transport a variety of aromatic acids as well as cis,cis-muconate []. 4-hydroxybenzoate transporter (PcaK Ppu), a member of this family, has been implicated in chemotaxis, allowing the bacteria to swim up concentration gradients of its substrates []. This is the only documented case where an MFS protein apparently serves as a chemoreceptor. One of the AAHS proteins (BenK Aca) transports benzoate []. Under the transporter classification (TC) system [], this family is classified as TC number 2.A.1.15.

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

1 Contains

Id Name Short Name Type
IPR005829 Sugar transporter, conserved site Sugar_transporter_CS Conserved_site

0 Found In

1 Parent Features

Id Name Short Name Type
IPR011701 Major facilitator superfamily MFS Family

5 Publications

First Author Title Year Journal Volume Pages
Saier MH Jr A functional-phylogenetic classification system for transmembrane solute transporters. 2000 Microbiol Mol Biol Rev 64 354-411
Pao SS Major facilitator superfamily. 1998 Microbiol Mol Biol Rev 62 1-34
Harwood CS Identification of the pcaRKF gene cluster from Pseudomonas putida: involvement in chemotaxis, biodegradation, and transport of 4-hydroxybenzoate. 1994 J Bacteriol 176 6479-88
Williams PA mucK, a gene in Acinetobacter calcoaceticus ADP1 (BD413), encodes the ability to grow on exogenous cis,cis-muconate as the sole carbon source. 1997 J Bacteriol 179 5935-42
Collier LS benK encodes a hydrophobic permease-like protein involved in benzoate degradation by Acinetobacter sp. strain ADP1. 1997 J Bacteriol 179 5943-6

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)