InterPro : IPR012752

Name  TDP-D-fucosamine acetyltransferase WecD Short Name  AcTrfase_WecD
Type  Family Description  This entry represents the WecD protein (also known as RffC), a TDP-fucosamine acetyltransferase involved in Enterobacterial common antigen (ECA) synthesis []. ECA is a family-specific surface antigen (polysaccharide) shared by all members of the Enterobacteriaceae and is restricted to this family []. ECA has been linked to the resistance of Salmonella enterica to bile salts, however, its function is unclear []. WecD is also a member of the GNAT (the GCN5-relatedN-acetyltransferase) family [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

2 Contains

Id Name Short Name Type
IPR002110 Ankyrin repeat Ankyrin_rpt Repeat
IPR000182 GNAT domain GNAT_dom Domain

0 Found In

0 Parent Features

3 Publications

First Author Title Year Journal Volume Pages
Hung MN Crystal structure of TDP-fucosamine acetyltransferase (WecD) from Escherichia coli, an enzyme required for enterobacterial common antigen synthesis. 2006 J Bacteriol 188 5606-17
Ramos-Morales F Role for Salmonella enterica enterobacterial common antigen in bile resistance and virulence. 2003 J Bacteriol 185 5328-32
Kuhn HM ECA, the enterobacterial common antigen. 1988 FEMS Microbiol Rev 4 195-222

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)