InterPro : IPR016451

Name  Intermediate filament, ifa/ifb Short Name  Intermed_filament_ifa/ifb
Type  Family Description  Intermediate filaments (IF) [, , ]are proteins which are primordial components of the cytoskeleton and the nuclear envelope. All IF proteins are structurally similar in that they consist of: a central rod domain comprising some 300 to 350 residues which is arranged in coiled-coiled alpha-helices, with at least two short characteristic interruptions; a N-terminal non-helical domain (head) of variable length; and a C-terminal domain (tail) which is also non-helical, and which shows extreme length variation between different IF proteins. While IF proteins are evolutionary and structurally related, they have limited sequence homologies except in several regions of the rod domain.This entry represents a family of cytoplasmic intermediate filament proteins of invertebrates, and includes both A and B types [, ].
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Sequence Features

GO Displayer

Proteins

InterPro protein domain ID --> Contigs

 

Other

0 Child Features

2 Contains

Id Name Short Name Type
IPR001322 Lamin Tail Domain Lamin_tail_dom Domain
IPR018039 Intermediate filament protein, conserved site Intermediate_filament_CS Conserved_site

0 Found In

1 Parent Features

Id Name Short Name Type
IPR001664 Intermediate filament protein IF Family

5 Publications

First Author Title Year Journal Volume Pages
Quinlan R Intermediate filament proteins. 1995 Protein Profile 2 795-952
Steinert PM Molecular and cellular biology of intermediate filaments. 1988 Annu Rev Biochem 57 593-625
Stewart M Intermediate filaments: structure, assembly and molecular interactions. 1990 Curr Opin Cell Biol 2 91-100
Weber K Cytoplasmic intermediate filament proteins of invertebrates are closer to nuclear lamins than are vertebrate intermediate filament proteins; sequence characterization of two muscle proteins of a nematode. 1989 EMBO J 8 3221-7
Karabinos A Essential roles for four cytoplasmic intermediate filament proteins in Caenorhabditis elegans development. 2001 Proc Natl Acad Sci U S A 98 7863-8



To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)