InterPro : IPR023521

Name  Translation release factor pelota, archaea Short Name  Pelota_arc
Type  Family Description  Proteins in this entry are archaeal homologues of the eukaryotic gene pelota (DOM34 in yeast), which functions in recognising stalled ribosomes []. In eukaryotes, eRF3 and HBS1, which are homologous to the tRNA carrier GTPase EF1-alpha, respectively bind eRF1 and Pelota. In Archaea eRF1 (aRF1) and Pelota (aPelota) homologues exist, but no orthologues of eRF3 and Hbs1 have been detected. Instead, it seems that archaeal EF1-alpha (aEF1-alpha) could serve as a carrier GTPase protein for both aRF1 and aPelota onto the ribosome [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

0 Contains

0 Found In

1 Parent Features

Id Name Short Name Type
IPR004405 Translation release factor pelota Transl_rel_pelota Family

2 Publications

First Author Title Year Journal Volume Pages
Saito K Omnipotent role of archaeal elongation factor 1 alpha (EF1α in translational elongation and termination, and quality control of protein synthesis. 2010 Proc Natl Acad Sci U S A 107 19242-7
Lee HH Structural and functional insights into Dom34, a key component of no-go mRNA decay. 2007 Mol Cell 27 938-50

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)