InterPro : IPR016263

Name  RNA polymerase sporulation-specific sigma factor, SigK/SigE Short Name  RNA_pol_sigma-SigE/K
Type  Family Description  This entry represents RNA polymerase sporulation-specific sigma factors, including SigK and SigE. Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. Gene regulation during Bacillus sporulation involves the activation and inactivation of multiple sigma subunits of RNA polymerase in a cascade. In the mother cell compartment of sporulating Bacillus cells, expression of the sigE gene, encoding the earlier-acting sigma factor, sigmaE, is negatively regulated by the later-acting sigma factor, sigmaK [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



2 Child Features

Id Name Short Name Type
IPR014200 RNA polymerase sigma-E type RNA_pol_sigma-E Family
IPR014209 RNA polymerase sigma-K type RNA_pol_sigma-K Family

5 Contains

Id Name Short Name Type
IPR011991 Winged helix-turn-helix DNA-binding domain WHTH_DNA-bd_dom Domain
IPR013325 RNA polymerase sigma factor, region 2 RNA_pol_sigma_r2 Domain
IPR007627 RNA polymerase sigma-70 region 2 RNA_pol_sigma70_r2 Domain
IPR000943 RNA polymerase sigma-70 RNA_pol_sigma70 Domain
IPR007630 RNA polymerase sigma-70 region 4 RNA_pol_sigma70_r4 Domain

0 Found In

0 Parent Features

1 Publications

First Author Title Year Journal Volume Pages
Zhang B sigmaK can negatively regulate sigE expression by two different mechanisms during sporulation of Bacillus subtilis. 1999 J Bacteriol 181 4081-8

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)