InterPro : IPR028358

Name  GDP-mannose 6-dehydrogenase Short Name  GDPman_DH
Type  Family Description  GDP-mannose 6-dehydrogenase catalyses the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerisation. The alginate layer is essential for cyst or protective biofilm formation in some bacteria [, ].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

0 Contains

0 Found In

1 Parent Features

Id Name Short Name Type
IPR017476 UDP-glucose/GDP-mannose dehydrogenase UDP-Glc/GDP-Man Family

2 Publications

First Author Title Year Journal Volume Pages
Snook CF Crystal structure of GDP-mannose dehydrogenase: a key enzyme of alginate biosynthesis in P. aeruginosa. 2003 Biochemistry 42 4658-68
Campos M Characterization of the gene coding for GDP-mannose dehydrogenase (algD) from Azotobacter vinelandii. 1996 J Bacteriol 178 1793-9

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)