InterPro : IPR028373

Name  Ski-related oncogene Sno Short Name  Ski-rel_Sno
Type  Family Description  Ski-like protein or ski-related oncogene Sno may have regulatory role in cell division or differentiation in response to extracellular signals [, ]. Four isoforms of the Sno protein have been identified, with the longest isoform known as SnoN. SnoN, as part of a histone deacetylase complex, binds to Smad proteins and blocks its ability to transduce TGF-beta signals [, , ].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

0 Contains

0 Found In

1 Parent Features

Id Name Short Name Type
IPR023216 Transcription regulator SKI/SnoN Tscrpt_reg_SKI_SnoN Family

5 Publications

First Author Title Year Journal Volume Pages
Komuro A Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1). 2004 Oncogene 23 6914-23
Pot I SnoN in TGF-beta signaling and cancer biology. 2008 Curr Mol Med 8 319-28
Pearson-White S Proto-oncogene Sno expression, alternative isoforms and immediate early serum response. 1997 Nucleic Acids Res 25 2930-7
Liu X Ski/Sno and TGF-beta signaling. 2001 Cytokine Growth Factor Rev 12 1-8
Stroschein SL Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein. 1999 Science 286 771-4

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)